Associate Director, Clinical Solutions Engineering

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity:

• Clinical Solutions Leadership: Lead the development and implementation of in-house applications, analytics, and AI-enabled solutions that support other clinical functions. Combine hands-on technical leadership with team management and delivery oversight to build reliable, scalable capabilities.

• Team Management and Development: Manage and mentor engineers, programmers, and technical contractors. Establish clear goals, provide regular feedback and coaching, support career development, and build a collaborative team culture grounded in technical excellence, accountability, and continuous learning.

• Solution Strategy and Delivery: Partner with functional leaders to define clinical solutions roadmap, prioritize business needs, and translate requirements into achievable implementation plans. Oversee project scope, resources, timelines, dependencies, and delivery risks while balancing new development and ongoing support.

• Dashboard and Application Development: Lead and contribute to the development of applications, dashboards, reports, backend dataflows, and data transformations that support clinical trial data review, analysis, performance metrics, and operational insights.

• AI Solution Architecture: Guide the design and delivery of scalable AI solutions and governed automation in regulated environments. Establish appropriate approaches for model selection, retrieval, prompt engineering, tool integration, evaluation, guardrails, and human review.

• AI Agent Development: Oversee and contribute to the development of Retrieval-Augmented Generation (RAG) agents and LLM-enabled applications supporting multi-step workflows, including study document review, specification interpretation, script generation, data mapping, reporting, output verification, and documentation.

• Programming and Workflow Modernization: Lead approaches for translating, modernizing, and validating analytical code across programming languages, with emphasis on SAS-to-R conversion and modernization of legacy workflows. Establish methods to demonstrate analytical equivalence, reproducibility, and traceability.

• Clinical Data and System Integration: Collaborate with Clinical Systems, IT, and business stakeholders to integrate solutions into clinical data platforms, statistical computing environments, and operational systems. Guide technical design decisions and support effective implementation and adoption.

• Technical Leadership and Knowledge Sharing: Remain actively involved in architecture, prototyping, code review, and resolution of complex technical issues. Develop reusable frameworks, promote sound engineering practices, and provide training and mentoring that strengthen team capabilities.

Required Skills, Experience and Education:

• Bachelor’s degree in Computer Science, Engineering, Data Science, Statistics, Bioinformatics, Health Informatics, or a related technical field; advanced degree preferred.

• 9+ years of progressive experience in software engineering, data engineering, statistical programming, clinical systems, AI/ML engi...