Vice President, Portfolio Sales and Field Team

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity:The Vice President, Oncology Sales will lead the design, build, and execution of a high-performing, national oncology sales organization supporting Revolution Medicines products/services to the oncology communityg. Reporting to the SVP of US Marketing & Field, the VP will be responsible for creating and scaling a best-in-class sales organization, ensuring successful product launches, and driving sustained revenue growth. This leader will combine strategic vision with operational rigor, leveraging deep oncology expertise and cross-functional collaboration to position the organization for long-term success.

Key Responsibilities:Organizational Build & Leadership

• Architect and execute the build-out of a national portfolio oncology sales organization, including hiring, onboarding, and development of regional leaders, account directors, and sales representatives.

• This will include nurse educator and other field facing roles or functions including sales operations and training.

• Establish organizational structure, roles, and deployment strategy aligned to brand objectives and market dynamics.

• Foster a high-performance culture grounded in accountability, collaboration, innovation, and patient-centricity.

• Develop leadership bench strength through coaching, succession planning, and talent development initiatives.

Strategic & Commercial Leadership

• Define and execute the national sales strategy across oncology indications, ensuring alignment with corporate objectives and brand strategies.

• Lead all aspects of product launch readiness and execution, including field deployment, targeting, messaging alignment, and performance tracking.

• Partner with Commercial Leadership Team to shape enterprise-wide strategy, providing field insights and actionable recommendations.

• Drive achievement of all revenue and performance targets, ensuring consistent delivery against quarterly and annual goals.

Sales Operations & Execution Excellence

• Oversee development and execution of key commercial levers including: Forecasting and demand planning, Incentive compensation design, Territory alignment and targeting, Performance analytics and reporting, Training and capability development programs.

• Ensure disciplined execution of business plans and continuous optimization based on market feedback and data insights.

Key Account & Market Engagement

• Lead strategy and executive engagement for top national accounts, including major health systems, IDNs, oncology networks, and GPOs.

• Oversee development and execution of strategic account plans that drive access, adoption, and long-term partnerships.

• Serve as a senior external representative of the company with key stakeholders and decision-makers.

Cross-Functional Collaboration

• Partner closely with Marketing, Market Access, Medical Affairs, Commercial Operations, and Training to ensure aligned execution.

• Lead cross-functional initiatives to address business challenges, optimize launch performance, and enhance c...