Senior Director, Global People Operations

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity:

The Senior Director, Global People Operations will evolve and lead the Global People Operations function required for a rapidly scaling global biopharmaceutical company. This leader will translate the company’s growth trajectory into an effective operating model that defines our consistent HR service & delivery approach and creates an effective global Revolutionary experience while balancing regional complexity and nuance.

Given our growth trajectory thus far, we have the opportunity to build People Operations with AI and automation embedded in how we design and deliver services to enable the experience of employees and managers. This is an opportunity to rethink processes from the ground up, using technology to make support easier, more responsive, and more effective while creating more capacity for work that requires human expertise and care. The role will partner with People Technology & HR leaders to build the integrated service model that combines strong operational foundations, intuitive employee support, and thoughtful use of technology.

The role owns global service delivery, employee lifecycle operations and controls, global operating and compliance standards, process excellence and the integration of Global Mobility into the broader service model. It is accountable for the employee administrative lifecycle—including operational onboarding and offboarding, leaves and accommodations administration; employee records, data, and employment documentation; payroll coordination and benefits execution; policy administration; and mobility, immigration, and work-authorization administration. You will establish clear operational accountability and build strong partnerships across COEs, HRBPs, regional HR teams, Legal and other cross-functional teams to align strategy, apply judgment, manage exceptions and mitigate risk.

This is a build-and-run leadership role for a collaborative HR leader capable of building the processes and team needed to support the company’s current and future scale. The successful leader will evolve the operating system while ensuring that today’s operation continues to perform with accuracy, control and care.

Key responsibilities

Build the global operating model. In close collaboration with HR leaders, COEs, HRBPs, regional teams and cross-functional partners, define the Global People Operations charter, multi-year roadmap, organization design, investment priorities, decision rights and governance required to support approximately 3,000-5,000+ employees and continued geographic expansion, within the overall HR strategy and organization framework.

Evolve the employee-service model. Evolve the service model to define a Tier 0–3 model: self-service and AI-enabled guidance; a scalable knowledge architecture; centralized People Operations intake and case ownership; specialist resolution; and escalation to HRBPs, ER, COEs and Legal for judgment-heavy matters.

Own the employee administrative lifecycle. Set accountability, controls and operational service expectations across onboarding, offboarding, transfers, leaves, accommodations administration, benefits execution, payroll coordinati...