Senior Director, US Medical Affairs Strategy Lead, Gastrointestinal, Oncology and Emerging Indications

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity:

Reporting to the VP US Medical Affairs, the Senior Director, US Medical Affairs, will be responsible for developing and executing the US Medical Affairs (USMA) strategy and tactical plans with a focus on launch readiness and life cycle management for an individual asset in gastrointestinal (GI) and emerging indications. The successful candidate will have a proven track record of developing and driving medical strategy with a focus on effectively communicating key scientific data through publications, medical information, medical communications, and congress activities as well as gathering insights through Advisory Boards and Key Opinion Leader (KOL) engagements. They must work collaboratively with cross-functional counterparts in Development, Research and Commercial as well as other partners in the organization to design and implement a comprehensive GI strategy.

Required Skills, Experience and Education:

Develops and executes the USMA strategy and medical objectives including activities related to scientific engagement and communication, evidence generation, internal education, and patient advocacy.

Develops and executes a Health Care Professional (HCP) engagement strategy to gather insights to inform the medical strategy.

Acts as the US medical representative on cross-functional teams

Serves as a therapeutic area content expert.

Participates in the Global Medical Affairs Team (GMAT) and US Medical Affairs Team (USMAT) to execute medical strategies, contribute to the operations and oversight of medical activities, and work cross-functionally to support associated pre-launch activities.

Supports the execution of routine gap assessments leading to the development/refinement of a publication strategy, an evidence generation plan, and tactical plan as part of the overall USMA plan.

Provides medical leadership in scientific engagement activities with key external stakeholders through organizing and leading advisory boards, studies investigator interactions, congress activities, and peer-to-peer discussions with the goal of communicating scientific insights to internal teams to drive strategy.

Communicates clinical and scientific data to KOLs and other healthcare professionals through presentations, educational programs, and scientific discussions.

Represents various medical affairs functions in cross-functional strategy team meetings including Clinical and Safety sub-teams, Global Brand Team, Global Product Team, Patient Advocacy, Market Access, and other cross-functional strategic discussions.

Works closely with the Clinical and US MSL and Payor Health System Liaisons teams to provide enrollment, scientific, and engagement support to ensure clinical trials meet study timelines.

Partners with RWE strategy and Biomarker/CDx teams on related integrated evidence generation strategies and activities as part of the USMA Plan.

Works with the Patient Advocacy and Grants teams to incorporate the patient voice and define external medical education strategies for independent grants, respectively.

Provides medical support for medical congresses and collaborates across US and Global functions to develop, review, an...